Protonic pump inhibitors (PPIs) are the most prescribed drugs for acute and maintenance therapy of gastroesophageal reflux disease, H.pylori-eradication (in association with antibacterial therapy), for ulcers prevention and cure and, recently, for prevention of NSAIDs-induced gastropathy.The high prevalence of these acid-related disorders induces a
Changing the immune responses to allergens is the cornerstone of allergen immunotherapy.Allergen-specific immunotherapy that consists of repeated administration of increasing doses of allergen extract is potentially curative.The major inconveniences of allergen-specific immunotherapy include failure to modify immune responses, long-term treatment l
This paper presents the results of testing certain remote sensing indices (vegetation health index, temperature index, normalized drought difference index, and others).Multitemporal data of nine indices Wine Cooler from Sentinel-2 and MODIS satellites for the vegetation period over 5 years were used to simulate the spring wheat yield of the Experim
Identifying the small number of rare causal variants contributing to disease has beena major focus of investigation in recent years, but represents a formidable statisticalchallenge due to the rare frequencies with which Mugs these variants are observed.In thiscommentary we draw attention to a formal statistical framework, namely hierarchicalmodeli